|
KMID : 1098420070150060405
|
|
Korean Journal of Medicinal Crop Science
2007 Volume.15 No. 6 p.405 ~ p.410
|
|
|
Comparison of Anticancer and Immuno-Modulatory Activities in the different parts of the Acer mono Max. and Acer okamotoanum
|
|
Qadir Syed Abdul
Lee Hak-Ju
Kwon Min-Cheol
Lee Hyeon-Yong
Kim Cheol-Hee
Kang Ha-Young
Choi Don-Ha
|
|
|
Abstract
|
|
|
|
This study was performed to investigate anticancer activities and immuno modulatory activities in the several parts of the A. mono and A. okamotoanum. The cytotoxicity of 1 of the water extracts on normal human lung cell(HEL299) was < 19.5%. The anticancer activity of all extracts were increased in over 55% against AGS (stomach adenocarcinoma), A549 (lung adenocarcinoma), Hep3B (liver adenocarcinoma, and MCF-7 (breast adenocarcinoma) cells. The growth of human immune B and T cells was improved of A. mono and A. okamotoanum in adding 1.0 concentration. The secretion of the IL-6 and of human immune B and T cells was increased with all extracts of A. mono and A. okamotoanum. All extracts of. A. mono and A. okamotoanum increased NK cell growth. The results showed that the barks and woods extracts of A. mono and A. okamotoanum had useful biological activities. In addition, bark of A. okamotoanuim showed the highest anticancer and immune activities.
|
|
|
KEYWORD
|
|
|
Acer mono, Acer okamotoanum, anticancer activites, immune activity, cytokine, NK cell
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|